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2026 NFL · market snapshot Oct 10, 2026, 8:27 PM EDT

NFL Week 5 Picks Against the Spread.

New England Patriots has the largest current model-to-spread difference. Every number below is tied to the displayed market snapshot and a pregame model run.

Games on the slate
15
2025 straight up
60.1%
2025 ATS
81–82
2025 totals
81–80
AwayRaiders
AT
HomePatriots
Sunday · Oct 11 · 1:00 PM ET

New England Patriots 16–27

Win pick
Patriots 80%
ATS lean
NE -3.5
Total lean
Under 45.5

Market: LV +160 · NE -192 · total 45.5

Full game file →
AwayBrowns
AT
HomeJets
Sunday · Oct 11 · 1:00 PM ET

Cleveland Browns 23–19

Win pick
Browns 63%
ATS lean
CLE +2.5
Total lean
Over 39.5

Market: CLE +114 · NYJ -135 · total 39.5

Full game file →
AwayGiants
AT
HomeCommanders
Sunday · Oct 11 · 1:00 PM ET

New York Giants 25–22

Win pick
Giants 58%
ATS lean
NYG +3.5
Total lean
Over 41.5

Market: NYG +150 · WAS -180 · total 41.5

Full game file →
AwayEagles
AT
HomeJaguars
Sunday · Oct 11 · 9:30 AM ET

Jacksonville Jaguars 15–28

Win pick
Jaguars 85%
ATS lean
JAX -7.5
Total lean
Over 41.5

Market: PHI +310 · JAX -395 · total 41.5

Full game file →
AwayBengals
AT
HomeDolphins
Sunday · Oct 11 · 1:00 PM ET

Cincinnati Bengals 24–22

Win pick
Bengals 55%
ATS lean
MIA +7
Total lean
Over 43.5

Market: CIN -355 · MIA +280 · total 43.5

Full game file →
AwayVikings
AT
HomeSaints
Sunday · Oct 11 · 1:00 PM ET

Minnesota Vikings 25–18

Win pick
Vikings 70%
ATS lean
MIN -2.5
Total lean
Over 41.5

Market: MIN -130 · NO +110 · total 41.5

Full game file →
AwayBears
AT
HomePackers
Sunday · Oct 11 · 1:00 PM ET

Chicago Bears 26–20

Win pick
Bears 67%
ATS lean
CHI -1.5
Total lean
Pass

Market: CHI -130 · GB +110 · total 46.5

Full game file →
AwayBroncos
AT
HomeChargers
Sunday · Oct 11 · 4:05 PM ET

Denver Broncos 25–18

Win pick
Broncos 70%
ATS lean
DEN -3.5
Total lean
Pass

Market: DEN -192 · LAC +160 · total 41.5

Full game file →
AwayTexans
AT
HomeTitans
Sunday · Oct 11 · 1:00 PM ET

Houston Texans 26–16

Win pick
Texans 77%
ATS lean
HOU -7
Total lean
Over 37.5

Market: HOU -345 · TEN +275 · total 37.5

Full game file →
Away49ers
AT
HomeSeahawks
Sunday · Oct 11 · 4:25 PM ET

Seattle Seahawks 23–24

Win pick
Seahawks 51%
ATS lean
SF +3
Total lean
Pass

Market: SF +136 · SEA -162 · total 45.5

Full game file →
AwayColts
AT
HomeSteelers
Sunday · Oct 11 · 1:00 PM ET

Pittsburgh Steelers 23–24

Win pick
Steelers 53%
ATS lean
IND +3
Total lean
Over 43.5

Market: IND +124 · PIT -148 · total 43.5

Full game file →
AwayLions
AT
HomeCardinals
Sunday · Oct 11 · 4:25 PM ET

Detroit Lions 31–23

Win pick
Lions 71%
ATS lean
DET -5.5
Total lean
Pass

Market: DET -258 · ARI +210 · total 54.5

Full game file →
AwayRavens
AT
HomeFalcons
Sunday · Oct 11 · 8:20 PM ET

Atlanta Falcons 24–25

Win pick
Falcons 54%
ATS lean
BAL +3
Total lean
Over 43.5

Market: BAL +145 · ATL -175 · total 43.5

Full game file →
AwayBills
AT
HomeRams
Monday · Oct 12 · 8:15 PM ET

Los Angeles Rams 23–28

Win pick
Rams 64%
ATS lean
LAR -3.5
Total lean
Under 54.5

Market: BUF +150 · LAR -180 · total 54.5

Full game file →
AwayBuccaneers
AT
HomeCowboys
Thursday · Oct 8 · 8:15 PM ET

Final: Buccaneers 24, Cowboys 16

This game started before FTT's first prediction snapshot, so the page shows market context and the result when available without inventing a pregame pick.

Market: TB +400 · DAL -535 · total 49.5

Full game file →
Read the number

A model difference, not a promise.

FTT blends opponent-adjusted scoring margin, recent scoring, prior-season strength, site and rest. The market line is a separate input used only to calculate the displayed difference.

The same rules went 125–83 straight up, 81–82 ATS and 81–80 on totals across 208 games in the 2025 Weeks 5-18 walk-forward. The ATS and totals records were effectively coin flips; the displayed differences are research signals, not a proven wagering edge.

See the complete methodology →
Questions, answered

What are the best NFL Week 5 picks against the spread?

The page ranks the current model differences and shows the evidence for every game. A larger difference is a stronger model signal, not a guaranteed result.

Where do the odds and lines come from?

FTT reads the nflverse schedule release, stores the market snapshot time, and freezes each pregame record at kickoff. It does not scrape or name an individual sportsbook.

How does the FTT NFL model work?

The model blends opponent-adjusted scoring margin, recent points scored and allowed, prior-season strength, home field and rest. Market lines are shown for comparison, not used to create the team rating.

Do the picks update after kickoff?

No. Pregame projections and the attached line snapshot freeze at kickoff. Final scores then grade the archived call without rewriting it.