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NFL Week 10 · Sunday, Nov 15 · 4:25 PM ET

49ers vs. Cowboys prediction.

San Francisco 49ers is the FTT straight-up pick at 62% model probability. The projected score is SF 28, DAL 24.

Market snapshot: Nov 4, 2026, 8:35 PM EST. Pregame numbers freeze at kickoff and do not move after the result.

Away

San Francisco 49ers

28
Record
6-1
FTT rating
+3.6
Listed QB
Purdy
Home

Dallas Cowboys

24
Record
3-5
FTT rating
-1.9
Listed QB
Prescott
Model vs. market

The pick, spread and total in one view.

MarketListed numberFTT numberFTT leanDifference
WinnerDAL 36% marketDAL 38% modelSan Francisco 49ers -2052.7 points
SpreadDAL +3.5DAL +4Pass0.5 points
TotalO/U 53.551.5Under 53.52.0 points
Why the model landed here

Strength, scoring, site and rest.

San Francisco 49ers entered Week 10 at 6-1 with a +8.3 point differential per game. Dallas Cowboys entered at 3-5 and +0.8 per game.

Dallas Cowboys receives the model's 1.5-point home-field adjustment. The rest difference is even.

The scoring projection regresses both teams' current points scored and allowed toward their prior-season baselines. The opponent-adjusted rating caps individual game margins at 28 points so one blowout cannot dominate the board.

On the 2025 Weeks 5-18 walk-forward, these rules finished 125–83 straight up, 81–82 ATS and 81–80 on totals. The ATS and totals results were effectively coin flips.

Full slateWeek 10 predictions →Spread boardAll ATS differences →Totals boardAll over / unders →
Questions, answered

Who will win 49ers vs. Cowboys?

The FTT model picks San Francisco 49ers. Its projected score is SF 28, DAL 24.

What is the 49ers vs. Cowboys spread pick?

The model difference is under one point, so FTT passes at -3.5.

What is the 49ers vs. Cowboys over/under pick?

The model leans under 53.5, with a 2.0-point difference.

When were these odds captured?

The market snapshot was captured Nov 4, 2026, 8:35 PM EST. Odds can move, and FTT does not present the snapshot as a live sportsbook quote.